Southeast Asian Regional Centre For Tropical Biology (SEAMEO BIOTROP) Antiproliferation Activities of Indonesian Java Chili, Piper Retrofractum Vahl., Against Breast Cancer Cells (Mcf-7)

What we are
- - What we are
  - SEAMEO BIOTROP, or Southeast Asian Regional Centre for Tropical Biology, was established at 6 February 1968.
- - About Us
  - History
  - Organization
  - Governing Board
  - Vision, Mission, and goals
  - Program Thrusts
  - Our Logo
- - Facilities
  - Laboratories
  - Library
  - Dormitories
  - Conference Hall
  - Classrooms
  - Field Experimental Sites
  - Greenhouses
- - Expertise
  - Our Expertise
  - Location
  - Our Location
  - Linkages
  - List of MoU
What we do
- - BIOTROP's Program
  - The Centre offers trainings and other learning programs to a varied range of target participants. They are aimed at helping produce a cadre of improved human resources in Southeast Asia on various aspects of tropical biology that are capable of bringing innovation and growth in their areas of work toward contributing to the total sustainable development of their respective countries.
- - Research
  - About Research Program
  - Youth Environmental Outreach
  - Completed Research
  - Training and Learning Events
  - About Learning Programs
  - List of Training for 2021
- - Services
  - Visit Program
  - Internship Program
  - Consultancy
  - Special Programs
  - About IndoBIC
  - About MIT Program
  - About SMARTS-BE Program
Publications
- - BIOTROP Publications
  - Publishing a good quality publication SEAMEO BIOTROP vision of becoming the leading centre in tropical biology
- - Publications
  - Books
  - BIOTROP Courier
  - BIODIVERS
  - Annual Report
  - BIOTROPIA
  - Proceedings
  - Publication Request
  - Publication Request Status
- - Library
  - Online Catalog
  - BIOTROPIA Journal
  - About BIOTROPIA
- - Exhibitions
  - SEAMEO BIOTROP Exhibition
  - Media Coverage
  - Media Coverage List

MSc in IT for NRM
About MIT Program
BIOTROPIA Journal
BIOTROPIA Journal Website

Facility Service Forms
Permintaan Ruangan, Dormitory dan Convention Hall
Peminjaman Barang
Permintaan Kendaraan
Permohanan Perbaikan
Kebutuhan Software
Hasil Perbaikan

Close Quicklinks

Antiproliferation Activities of Indonesian Java Chili, Piper Retrofractum Vahl., Against Breast Cancer Cells (Mcf-7)
A. E. Z. Hasan, A. Setiyono, and J.J. Silip

Source: SEAMEO BIOTROP's Research Grant | 2014

Abstract:

Cancer is a major killer in the world. Breast cancer is the first rank in the number of patients treated in Indonesia (28%), followed by cervical cancer (12%). Piperine is an active component in Java chili fruit (Piper retrofractum Vahl.) that serves as an anticancer ingredient. By extracting fruit Java chili and tested in vitro against breast cancer cells MCF-7 by means of the MTT-assay. From fifth locations Java chilies example of this research. Based on the analysis of phytochemicals, all Java chili extract contains flavonoids and alkaloids in addition to steroids. Java chili fruits extract the highest anticancer activeness as indicated by the Java chili fruits extract derived from Air Naningan 2 Lampung with IC50 value of 4.35 µg/ml.

Key words : Java Chili, anticancer, Piper retrofractum, MCF-7

Download full report

Antiproliferation Activities of Indonesian Java Chili, Piper Retrofractum Vahl., Against Breast Cancer Cells (Mcf-7) A. E. Z. Hasan, A. Setiyono, and J.J. Silip

Share this:

Antiproliferation Activities of Indonesian Java Chili, Piper Retrofractum Vahl., Against Breast Cancer Cells (Mcf-7)
A. E. Z. Hasan, A. Setiyono, and J.J. Silip